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In a double blind, randomized trial involving 151 patients with ovarian cancer treated with cisplatin, intravenous glutathione therapy was shown to reduce the toxicity of cisplatin and improve quality of life

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Results N-acetylcysteine increased blood glutathione redox ratios in those with Parkinson’s and Gaucher disease and healthy controls, which was followed by an increase in brain glutathione concentrations in all subjects