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B12 (or cobalamin) is a water-soluble vitamin involved in supporting the normal function of your nerve cells and is needed for red blood cell formation and DNA synthesis. It | Advanced Skin Cheltenham

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The proteins were embedded in a box of OPC water molecules (minimum distance of 12 Å from the solute to the boundaries of the box) and the net charge of the system was set to zero by neutralization with Cl-ions using the program tLEaP included in AmberTools21 ( 60