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Similarly, although hepatic dysfunction can occur with large niacin doses (1-3 grams daily over months) causing elevated liver enzymes or jaundice, niacinamide at 100 mg is very unlikely to have any adverse effect on the liver

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Recommendations This guideline includes recommendations on: recognising vitamin B12 deficiency, including when to test for the condition diagnosing vitamin B12 deficiency identifying the cause of vitamin B12 deficiency, including autoimmune gastritis managing vitamin B12 deficiency ongoing care and follow up monitoring for gastric cancer in people with autoimmune gastritis information and support for people with suspected or confirmed vitamin B12 deficiency