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The dopa oxidase level in the UVB-irradiated group (10.907 ± 2.059 units/min) was significantly increased as compared with that in the vehicle control group (1.533 ± 0.349 units/min)

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What’s more, those who used a combination of SAP and 2% retinol — a vitamin A derivative — had a 63.1% reduction ( Though these results are promising, larger high-quality studies are needed