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Anyone can become dehydrated, but the risk is higher if you: Work outdoors in the heat Exercise regularly Spend long days on the golf course Coach or play outdoor sports Work in construction, landscaping, or farming Travel frequently Have vomiting or diarrhea Drink alcohol Take certain medications, including some diuretics Even spending a day at the lake can leave you more dehydrated than you realize

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This approach supports deeper analysis of differences between enzyme-targeted small molecules and peptide-based signaling models