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In contrast, idiosyncratic DILI is often described as being unpredictable and not dose-related (Ma et al., 2023)

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Symptoms often fluctuate with: Stress Diet Gut health Alcohol Heat exposure Hormonal shifts Sleep disruption Immune activation This pattern suggests something important: Rosacea is frequently a systemic inflammatory and neuroimmune condition with skin manifestations—not merely a cosmetic issue

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