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The researchers found that one variant in a mitochondrial gene (not in 23andMe or AncestryDNA) that lowers mitochondrial membrane potential when oxidative phosphorylation is required was associated with susceptibility to fibromyalgia

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found that the ketone bodies, especially β-hydroxybutyrate, which protects against lipotoxicity and stimulates lipid oxidation, was significantly elevated in obese subjects (28)