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Although the details differ for different Csp3s, the kinetics of Cu I binding are generally quite fast but only for an initial phase, with the kinetics of Cu I removal by a high affinity Cu(I) chelator very slow, beyond the first couple mol equivalents of Cu I
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doi: 10.3389/fphar.2023.1147414 Received 18 January 2023 Accepted 22 February 2023 Published 02 March 2023 Volume 14 - 2023 Edited by Zhihao Liu, Dalian Medical University, China Reviewed by Raúl Gonzalez Ojeda, University of Galway, Ireland Hang Liu, University of California, Los Angeles, United States Updates Copyright © 2023 Pei, Pan, Wei and Hua