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Meta-analysis The included studies showed substantial heterogeneity (I 2 = 99.6%, p 0.05), supporting the conclusion of comparable efficacy and the lack of a clear dose–response relationship

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This depletion can manifest itself in ways that might include impaired nutrient absorption and assimilation, gut, lung, eye, blood, skin, and brain issues, keloid scarring, mitochondrial stress for lower energy output, DNA mutation, mass oxidation, and free radical overload