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Sachse C, Smith G, Wilkie MJ, Barrett JH, Waxman R, Sullivan F, Forman D, Bishop DT, Wolf CR Colorectal Cancer Study G (2002) A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

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Our finding that there is only a small increase increase in covalent binding after a therapeutic dose, even with a four-fold increase in CYP P-450 activity supports this idea

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