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Patients with pure CARD9 deficiency often present with Familial chronic cutaneous and mucosal candidiasis (CMC), accompanied by stubborn infections in the skin, nails, and mouth, and some may have deep fungal diseases, making conventional treatment difficult to cure (Puel et al., 2012)

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Using a commercial cold pack or a homemade one (from crushed ice, ice cubes or a bag of frozen vegetables) can be helpful