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Scientific investigations also examine BPC-157 in relation to intracellular signaling pathways involving nitric oxide synthase (NOS) , FAK/paxillin signaling , ERK/MAPK pathways , PI3K/Akt signaling , transcriptional regulation, cytoskeletal organization, and peptide-mediated molecular communication
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In their reactive state, astrocytes undergo morphologic and functional remodeling, which alters their ability to provide synaptic and metabolic support to neurons 18,35